Structural and functional analysis of two glutamate racemase isozymes from Bacillus anthracis and implications for inhibitor design

Glutamate racemase (RacE) is responsible for converting L-glutamate to D-glutamate, which is an essential component of peptidoglycan biosynthesis, and the primary constituent of the poly-γ-D-glutamate capsule of the pathogen Bacillus anthracis. RacE enzymes are essential for bacterial growth and lac...

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Main Authors: May, Melissa, Mehboob, Shahila, Mulhearn, Debbie C., Wang, Zhiqiang, Yu, Huidong, Thatcher, Gregory R.J., Santarsiero, Bernard D., Johnson, Michael E., Mesecar, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736553/
https://ncbi.nlm.nih.gov/pubmed/17610893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.05.093
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