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Biochemical basis for the essential genetic requirements of RecA and the β-clamp in Pol V activation

In Escherichia coli, it is genetically well established that the β-clamp and RecA are essential cofactors that endow DNA polymerase (Pol) V with lesion bypass activity. However, the biochemical basis for these requirements is still largely unknown. Because the process of translesion synthesis (TLS)...

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Detalhes bibliográficos
Main Authors: Fujii, Shingo, Fuchs, Robert P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736454/
https://ncbi.nlm.nih.gov/pubmed/19706415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905855106
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