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Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels
WNK4 (with no lysine kinase 4) inhibits ROMK channel activity in the distal nephron by stimulating clathrin-dependent endocytosis, an effect attenuated by SGK1 (serum-glucocorticoids-induced kinase)-mediated phosphorylation. It has been suggested that increased ROMK activity because of SGK1-mediated...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736404/ https://ncbi.nlm.nih.gov/pubmed/19706464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907855106 |
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