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Mechanism of action of lenalidomide in hematological malignancies
Immunomodulatory drugs lenalidomide and pomalidomide are synthetic compounds derived by modifying the chemical structure of thalidomide to improve its potency and reduce its side effects. Lenalidomide is a 4-amino-glutamyl analogue of thalidomide that lacks the neurologic side effects of sedation an...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736171/ https://ncbi.nlm.nih.gov/pubmed/19674465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-2-36 |
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