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Mechanism of action of lenalidomide in hematological malignancies

Immunomodulatory drugs lenalidomide and pomalidomide are synthetic compounds derived by modifying the chemical structure of thalidomide to improve its potency and reduce its side effects. Lenalidomide is a 4-amino-glutamyl analogue of thalidomide that lacks the neurologic side effects of sedation an...

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Main Authors: Kotla, Venumadhav, Goel, Swati, Nischal, Sangeeta, Heuck, Christoph, Vivek, Kumar, Das, Bhaskar, Verma, Amit
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736171/
https://ncbi.nlm.nih.gov/pubmed/19674465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-2-36
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