Binding of pro-prion to filamin A disrupts cytoskeleton and correlates with poor prognosis in pancreatic cancer

The cellular prion protein (PrP) is a highly conserved, widely expressed, glycosylphosphatidylinositol-anchored (GPI-anchored) cell surface glycoprotein. Since its discovery, most studies on PrP have focused on its role in neurodegenerative prion diseases, whereas its function outside the nervous sy...

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Detalhes bibliográficos
Main Authors: Li, Chaoyang, Yu, Shuiliang, Nakamura, Fumihiko, Yin, Shaoman, Xu, Jinghua, Petrolla, Amber A., Singh, Neena, Tartakoff, Alan, Abbott, Derek W., Xin, Wei, Sy, Man-Sun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735930/
https://ncbi.nlm.nih.gov/pubmed/19690385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39542
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