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Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator–dependent bicarbonate secretion
The mechanisms underlying mucus-associated pathologies in cystic fibrosis (CF) remain obscure. However, recent studies indicate that CF transmembrane conductance regulator (CFTR) is required for bicarbonate (HCO(3)(–)) transport and that HCO(3)(–) is critical for normal mucus formation. We therefore...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735925/ https://ncbi.nlm.nih.gov/pubmed/19726884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38662 |
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