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Exendin-4 normalizes islet vascularity in intrauterine growth restricted rats: potential role of VEGF

Intrauterine growth restriction induced by uterine artery ligation in pregnant rats leads to low birth weight and early insulin secretory defects followed by the development of insulin resistance, decline in β-cell mass, and diabetes in adulthood. Neonatal administration of Exendin-4 (Ex-4) prevents...

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書誌詳細
主要な著者: Ham, J. Nina, Crutchlow, Michael F., Desai, Biva M., Simmons, Rebecca A., Stoffers, Doris A.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735861/
https://ncbi.nlm.nih.gov/pubmed/19287346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e3181a282a5
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