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Increasing expression of H- or L-ferritin protects cortical astrocytes from hemin toxicity

Iron toxicity may contribute to oxidative injury in cells surrounding an intracerebral hematoma. Cells detoxify iron by sequestering it in ferritin, a 24-mer heteropolymer constructed of H and L subunits. The relative antioxidant efficacy of H and L-ferritin has not been defined, and was tested in t...

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Detalhes bibliográficos
Main Authors: LI, ZHI, CHEN-ROETLING, JING, REGAN, RAYMOND F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735853/
https://ncbi.nlm.nih.gov/pubmed/19513908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10715760902942808
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