Autophagy Gene Variant IRGM −261T Contributes to Protection from Tuberculosis Caused by Mycobacterium tuberculosis but Not by M. africanum Strains

The human immunity-related GTPase M (IRGM) has been shown to be critically involved in regulating autophagy as a means of disposing cytosolic cellular structures and of reducing the growth of intracellular pathogens in vitro. This includes Mycobacterium tuberculosis, which is in agreement with findi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Intemann, Christopher D., Thye, Thorsten, Niemann, Stefan, Browne, Edmund N. L., Amanua Chinbuah, Margaret, Enimil, Anthony, Gyapong, John, Osei, Ivy, Owusu-Dabo, Ellis, Helm, Susanne, Rüsch-Gerdes, Sabine, Horstmann, Rolf D., Meyer, Christian G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735778/
https://ncbi.nlm.nih.gov/pubmed/19750224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000577
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