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Generation of pluripotent stem cells from patients with type 1 diabetes

Type 1 diabetes (T1D) is the result of an autoimmune destruction of pancreatic β cells. The cellular and molecular defects that cause the disease remain unknown. Pluripotent cells generated from patients with T1D would be useful for disease modeling. We show here that induced pluripotent stem (iPS)...

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Autors principals: Maehr, René, Chen, Shuibing, Snitow, Melinda, Ludwig, Thomas, Yagasaki, Lisa, Goland, Robin, Leibel, Rudolph L., Melton, Douglas A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735559/
https://ncbi.nlm.nih.gov/pubmed/19720998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906894106
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