Pancreatic lipase-related protein 2 (PLRP2) induction by IL-4 in cytotoxic T lymphocytes (CTLs) and reevaluation of the negative effects of its gene ablation on cytotoxicity

Pancreatic lipase-related protein 2 (PLRP2) is induced by IL-4 in vitro in cytotoxic T lymphocyte (CTL) clones and CTLs from immunized wild-type (WT) PLRP2(+/+) are more cytotoxic than PLRP2(−/−) CTLs, suggesting to previous investigators that the lipase PLRP2 might support CTL functions. Here, we f...

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Detalhes bibliográficos
Main Authors: Alves, Bryce N., Leong, Jeff, Tamang, David L., Elliott, Viki, Edelnant, Jillian, Redelman, Doug, Singer, Cherie A., Kuhn, Andrew R., Miller, Rita, Lowe, Mark E., Hudig, Dorothy
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2009
Assuntos:
Inflammation, Extracellular Mediators, & Effector Molecules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735286/
https://ncbi.nlm.nih.gov/pubmed/19451396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1208766
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