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The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice
We showed previously that Lyn is a substrate for caspases, a family of cysteine proteases, involved in the regulation of apoptosis and inflammation. Here, we report that expression of the caspase-cleaved form of Lyn (LynΔN), in mice, mediates a chronic inflammatory syndrome resembling human psoriasi...
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| 主要な著者: | , , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735179/ https://ncbi.nlm.nih.gov/pubmed/19590497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.183 |
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