Cyclophosphamide Chemotherapy Sensitizes Tumor Cells to TRAIL-Dependent CD8 T Cell-Mediated Immune Attack Resulting in Suppression of Tumor Growth

BACKGROUND: Anti-cancer chemotherapy can be simultaneously lymphodepleting and immunostimulatory. Pre-clinical models clearly demonstrate that chemotherapy can synergize with immunotherapy, raising the question how the immune system can be mobilized to generate anti-tumor immune responses in the con...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: van der Most, Robbert G., Currie, Andrew J., Cleaver, Amanda L., Salmons, Joanne, Nowak, Anna K., Mahendran, Sathish, Larma, Irma, Prosser, Amy, Robinson, Bruce W. S., Smyth, Mark J., Scalzo, Anthony A., Degli-Esposti, Mariapia A., Lake, Richard A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734989/
https://ncbi.nlm.nih.gov/pubmed/19746156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006982
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