Noninvasive Monitoring of HPMA Copolymer–RGDfK Conjugates by Magnetic Resonance Imaging

PURPOSE: To evaluate the tumor targeting potential of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer–gadolinium(Gd)–RGDfK conjugates by magnetic resonance (MR) T1-mapping. METHODS: HPMA copolymers with and without RGDfK were synthesized to incorporate side chains for Gd chelation. The conjugates...

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Hlavní autoři: Zarabi, Bahar, Borgman, Mark P., Zhuo, Jiachen, Gullapalli, Rao, Ghandehari, Hamidreza
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734971/
https://ncbi.nlm.nih.gov/pubmed/19160028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-9830-5
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