Safety and Immunological Efficacy of a DNA Vaccine Encoding Prostatic Acid Phosphatase in Patients With Stage D0 Prostate Cancer

PURPOSE: Prostatic acid phosphatase (PAP) is a prostate tumor antigen. We have previously demonstrated that a DNA vaccine encoding PAP can elicit antigen-specific CD8+ T cells in rodents. We report here the results of a phase I/IIa trial conducted with a DNA vaccine encoding human PAP in patients wi...

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Detalhes bibliográficos
Main Authors: McNeel, Douglas G., Dunphy, Edward J., Davies, James G., Frye, Thomas P., Johnson, Laura E., Staab, Mary Jane, Horvath, Dorothea L., Straus, Jane, Alberti, Dona, Marnocha, Rebecca, Liu, Glenn, Eickhoff, Jens C., Wilding, George
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2009
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734418/
https://ncbi.nlm.nih.gov/pubmed/19636017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.19.9968
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