Real-Time Immune Monitoring to Guide Plasmid DNA Vaccination Schedule Targeting Prostatic Acid Phosphatase (PAP) in Patients with Castration-Resistant Prostate Cancer

BACKGROUND: We have previously reported that a DNA vaccine encoding prostatic acid phosphatase (PAP) could elicit PAP-specific T cells in patients with early recurrent prostate cancer. In the current pilot trial we sought to evaluate whether prolonged immunization with regular booster immunizations,...

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Bibliographic Details
Main Authors: McNeel, Douglas G., Becker, Jordan T., Eickhoff, Jens C., Johnson, Laura E., Bradley, Eric, Pohlkamp, Isabel, Staab, Mary Jane, Liu, Glenn, Wilding, George, Olson, Brian M.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102643/
https://ncbi.nlm.nih.gov/pubmed/24850844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0169
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