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Alloreactive CD8 T cell tolerance requires recipient B cells, dendritic cells and MHC class II

Allogeneic bone marrow chimerism induces robust systemic tolerance to donor alloantigens. Achievement of chimerism requires avoidance of marrow rejection by pre-existing CD4 and CD8 T cells, either of which can reject fully MHC-mismatched marrow. Both barriers are overcome with a minimal regimen inv...

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Autors principals: Fehr, Thomas, Haspot, Fabienne, Mollov, Joshua, Chittenden, Meredith, Hogan, Timothy, Sykes, Megan
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734139/
https://ncbi.nlm.nih.gov/pubmed/18566381
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