The cyclin dependent kinase domain of p21 is a suppressor of IL-1β-mediated inflammation in activated macrophages

Significant morbidity and mortality can be attributed to inflammatory diseases; therefore, a greater understanding of the mechanisms involved in the progression of inflammation is crucial. Here we demonstrate that p21((WAF1/CIP1)), an established suppressor of cell cycle progression, is an inhibitor...

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Hlavní autoři: Scatizzi, John C., Mavers, Melissa, Hutcheson, Jack, Young, Brittany, Shi, Bo, Pope, Richard M., Ruderman, Eric M., Samways, Damien S.K., Corbett, John A., Egan, Terrance M., Perlman, Harris
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734089/
https://ncbi.nlm.nih.gov/pubmed/19189309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838683
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