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Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons

Mitochondria exist as dynamic networks that are constantly remodeled through the opposing actions of fusion and fission proteins. Changes in the expression of these proteins alter mitochondrial shape and size, and may promote or inhibit the propagation of apoptotic signals. Using mitochondrially tar...

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Библиографические подробности
Главные авторы: Uo, Takuma, Dworzak, Jenny, Kinoshita, Chizuru, Inman, Denise M., Kinoshita, Yoshito, Horner, Philip J., Morrison, Richard S.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733949/
https://ncbi.nlm.nih.gov/pubmed/19445933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.05.010
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