Gene Expression Profiling of Aging in Multiple Mouse Strains: Identification of Aging Biomarkers and Impact of Dietary Antioxidants

We used DNA microarrays to identify panels of transcriptional markers of aging that are differentially expressed in young (5-month) and old (25-month) mice of multiple inbred strains (129sv, BALB/c, CBA, DBA, B6, C3H, and B6C3F(1)). In the heart, age-related changes of five genes were studied throug...

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Autori principali: Park, Sang-Kyu, Kim, Kyoungmi, Page, Grier P., Allison, David B., Weindruch, Richard, Prolla, Tomas A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733852/
https://ncbi.nlm.nih.gov/pubmed/19555370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2009.00496.x
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