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Differential effect of α- and γ-tocopherol supplementation in age-related transcriptional alterations in heart and brain of B6/C3H F1 mice

To investigate the global effects of vitamin E supplementation on aging, we used high-density oligonucleotide arrays to measure transcriptional alterations in the heart and brain (neocortex) of 30-month-old B6C3F(1) mice supplemented with α- and γ-tocopherol since middle age (15 months). Gene expres...

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Autors principals: Park, Sang-Kyu, Page, Grier P., Kim, Kyoungmi, Allison, David B., Meydani, Mohsen, Weindruch, Richard, Prolla, Tomas A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768425/
https://ncbi.nlm.nih.gov/pubmed/18492827
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