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AURKB-mediated effects on chromatin regulate binding versus release of XIST RNA to the inactive chromosome
How XIST RNA strictly localizes across the inactive X chromosome is unknown; however, prophase release of human XIST RNA provides a clue. Tests of inhibitors that mimic mitotic chromatin modifications implicated an indirect role of PP1 (protein phosphatase 1), potentially via its interphase repressi...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2733744/ https://ncbi.nlm.nih.gov/pubmed/19704020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200811143 |
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