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Analysis of the MTHFD1 promoter and risk of neural tube defects

Genetic variants in MTHFD1 (5,10-methylenetetrahydrofolate dehydrogenase/ 5,10-methenyltetrahydrofolate cyclohydrolase/ 10-formyltetrahydrofolate synthetase), an important folate metabolic enzyme, are associated with a number of common diseases, including neural tube defects (NTDs). This study inves...

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Detalhes bibliográficos
Main Authors: Carroll, Nicola, Pangilinan, Faith, Molloy, Anne M., Troendle, James, Mills, James L., Kirke, Peadar N., Brody, Lawrence C., Scott, John M., Parle-McDermott, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732995/
https://ncbi.nlm.nih.gov/pubmed/19130090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-008-0616-3
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