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Replication and exploratory analysis of 24 candidate risk polymorphisms for neural tube defects

BACKGROUND: Neural tube defects (NTDs), which are among the most common congenital malformations, are influenced by environmental and genetic factors. Low maternal folate is the strongest known contributing factor, making variants in genes in the folate metabolic pathway attractive candidates for NT...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Main Authors: Pangilinan, Faith, Molloy, Anne M, Mills, James L, Troendle, James F, Parle-McDermott, Anne, Kay, Denise M, Browne, Marilyn L, McGrath, Emily C, Abaan, Hatice Ozel, Sutton, Marie, Kirke, Peadar N, Caggana, Michele, Shane, Barry, Scott, John M, Brody, Lawrence C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411759/
https://ncbi.nlm.nih.gov/pubmed/25293959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-014-0102-9
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