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TPMT*26 (208F→L), a novel mutation detected in a Chinese

AIMS: Azathioprine, mercaptopurine and thioguanine are commonly used to treat autoimmune disorders, leukaemia and solid organ transplantation. However, azathiopurine and its metabolites can also cause adverse reactions such as myelosuppression. These manifestations may be attributed to polymorphisms...

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Autori principali: Kham, Shirley Kow Yin, Soh, Chin Kok, Aw, Derrick Chen Wee, Yeoh, Allen Eng Juh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732947/
https://ncbi.nlm.nih.gov/pubmed/19660010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03405.x
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