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The first Chinese case of Creutzfeldt-Jakob disease patient with R208H mutation in PRNP

A case of Creutzfeldt-Jakob disease (CJD) with a rare mutation of the prion protein (PrP) gene (PRNP) at codon 208 (R208H), while the codon 129 was a methionine homozygous genotype is reported. The patient initial displayed hand tremor, dizziness and progressive cognitive dysfunction. Subsequently,...

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Detalhes bibliográficos
Main Authors: Chen, Cao, Shi, Qi, Tian, Chan, Li, Qing, Zhou, Wei, Gao, Chen, Han, Jun, Dong, Xiao-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226051/
https://ncbi.nlm.nih.gov/pubmed/21791975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.3.16796
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