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Effects of CYP2D6 genotypes on age-related change of flecainide metabolism: involvement of CYP1A2-mediated metabolism

AIMS: The aim of this study was to clarify the effects of CYP2D6 genotype on age-related change in flecainide metabolism in patients with supraventricular tachyarrhythmias. An in vitro study using microsomes was performed to identify other CYPs responsible for age-related change in flecainide metabo...

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Hlavní autoři: Doki, Kosuke, Homma, Masato, Kuga, Keisuke, Aonuma, Kazutaka, Kohda, Yukinao
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732943/
https://ncbi.nlm.nih.gov/pubmed/19660006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03435.x
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