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Protein kinases mediate ligand-independent derepression of sumoylated progesterone receptors in breast cancer cells
In advanced breast tumors, protein kinases are upregulated and steroid hormone receptors often function independently of ligand. Herein, we explored mechanisms of ligand-independent progesterone receptor (PR) activity. We showed previously that growth factor-induced phosphorylation of PR Ser-294 blo...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732858/ https://ncbi.nlm.nih.gov/pubmed/19706513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905118106 |
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