Linkage of Progestin and Epidermal Growth Factor Signaling: Phosphorylation of Progesterone Receptors Mediates Transcriptional Hypersensitivity and Increased Ligand-Independent Breast Cancer Cell Growth

Progesterone receptor (PR) action is linked to epidermal growth factor (EGF) initiated signaling pathways at multiple levels; mitogen-activated protein kinases (MAPKs) are key mediators of this important cross-talk. Herein, we probed the effects of EGF on PR function and regulation of breast cancer...

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Detalhes bibliográficos
Main Authors: Daniel, Andrea R., Qiu, Ming, Faivre, Emily J., Ostrander, Julie Hanson, Skildum, Andrew, Lange, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850618/
https://ncbi.nlm.nih.gov/pubmed/17173941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2006.11.009
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