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Uncoupling CD21 and CD19 of the B-cell coreceptor
Complement receptors (CRs) CD21 and CD35 form a coreceptor with CD19 and CD81 on murine B cells that when coligated with the B-cell receptor lowers the threshold of activation by several orders of magnitude. This intrinsic signaling role is thought to explain the impaired humoral immunity of mice be...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732852/ https://ncbi.nlm.nih.gov/pubmed/19706534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903477106 |
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