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Structural and functional analysis of Nup120 suggests ring formation of the Nup84 complex

The Nup84 complex constitutes a key building block in the nuclear pore complex (NPC). Here we present the crystal structure of one of its 7 components, Nup120, which reveals a β propeller and an α-helical domain representing a novel fold. We discovered a previously unidentified interaction of Nup120...

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Détails bibliographiques
Auteurs principaux: Seo, Hyuk-Soo, Ma, Yingli, Debler, Erik W., Wacker, Daniel, Kutik, Stephan, Blobel, Günter, Hoelz, André
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732846/
https://ncbi.nlm.nih.gov/pubmed/19706512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907453106
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