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Crystal structure of the N-terminal domain of the human protooncogene Nup214/CAN

The mammalian nuclear pore complex (NPC) is an ≈120-MDa proteinaceous assembly consisting of ≈30 proteins and is the sole gate in the nuclear envelope. The human protooncogene Nup214 was first identified as a target for chromosomal translocation involved in leukemogenesis. Nup214 is located on the c...

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Detalhes bibliográficos
Main Authors: Napetschnig, Johanna, Blobel, Günter, Hoelz, André
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794303/
https://ncbi.nlm.nih.gov/pubmed/17264208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610828104
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