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(−)-Epigallocatechin-3-gallate Inhibits Hsp90 Function by Impairing Hsp90 Association with Co-chaperones in Pancreatic Cancer Cell Line Mia Paca-2

(−)-Epigallocatechin-3-gallate [(−)-EGCG], the most abundant polyphenolic catechin in green tea, showed chemoprevention and anticancer activities. (−)-EGCG was reported to bind to the C-terminal domain of heat shock protein 90 (Hsp90). The purpose of this study is to investigate (−)-EGCG as a novel...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Li, Yanyan, Zhang, Tao, Jiang, Yiqun, Lee, Hsiu-Fang, Schwartz, Steven J., Sun, Duxin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732434/
https://ncbi.nlm.nih.gov/pubmed/19438225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900037p
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