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Removal of either N-glycan site from the envelope receptor binding domain of Moloney and Friend but not AKV mouse ecotropic gammaretroviruses alters receptor usage

Three N-linked glycosylation sites were removed from the envelope glycoproteins of Friend, Moloney, and AKV mouse ecotropic gammaretroviruses: gs1 and gs2, in the receptor binding domain; and gs8, in a region implicated in post-binding cell fusion. Mutants were tested for their ability to infect rod...

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Detalhes bibliográficos
Main Authors: Knoper, Ryan C., Ferrarone, John, Yan, Yuhe, Lafont, Bernard A. P., Kozak, Christine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732407/
https://ncbi.nlm.nih.gov/pubmed/19584017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.06.015
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