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Second site mutation in the virus envelope expands the host range of a cytopathic variant of Moloney murine leukemia virus
Spl574 MLV (murine leukemia virus) is a variant of Moloney ecotropic MLV (MoMLV) that is cytopathic in Mus dunni cells and restricted by other mouse cells. Its host range and cytopathicity are due to a mutation, S82F, at a site critical for binding to the CAT-1 receptor. To identify residues that af...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3444676/ https://ncbi.nlm.nih.gov/pubmed/22835818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.06.031 |
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