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Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic mouse gammaretroviruses

BACKGROUND: We previously identified unusual variants of Moloney and Friend ecotropic mouse gammaretroviruses that have altered host range and are cytopathic in cells of the wild mouse species Mus dunni. Cytopathicity was attributed to different amino acid substitutions at the same critical env resi...

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Autors principals: Yan, Yuhe, Jung, Yong T, Wu, Tiyun, Kozak, Christine A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248597/
https://ncbi.nlm.nih.gov/pubmed/18186934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-2
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