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Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic mouse gammaretroviruses

BACKGROUND: We previously identified unusual variants of Moloney and Friend ecotropic mouse gammaretroviruses that have altered host range and are cytopathic in cells of the wild mouse species Mus dunni. Cytopathicity was attributed to different amino acid substitutions at the same critical env resi...

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Hlavní autoři: Yan, Yuhe, Jung, Yong T, Wu, Tiyun, Kozak, Christine A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248597/
https://ncbi.nlm.nih.gov/pubmed/18186934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-2
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