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Reduced amino acid alphabets exhibit an improved sensitivity and selectivity in fold assignment

Motivation: Many proteins with vastly dissimilar sequences are found to share a common fold, as evidenced in the wealth of structures now available in the Protein Data Bank. One idea that has found success in various applications is the concept of a reduced amino acid alphabet, wherein similar amino...

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Detalhes bibliográficos
Main Authors: Peterson, Eric L., Kondev, Jané, Theriot, Julie A., Phillips, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732308/
https://ncbi.nlm.nih.gov/pubmed/19351620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp164
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