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Reduced alphabet of prebiotic amino acids optimally encodes the conformational space of diverse extant protein folds

BACKGROUND: There is wide agreement that only a subset of the twenty standard amino acids existed prebiotically in sufficient concentrations to form functional polypeptides. We ask how this subset, postulated as {A,D,E,G,I,L,P,S,T,V}, could have formed structures stable enough to found metabolic pat...

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Bibliografiska uppgifter
I publikationen:BMC Evol Biol
Huvudupphovsman: Solis, Armando D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668081/
https://ncbi.nlm.nih.gov/pubmed/31362700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-019-1464-6
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