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Reduced amino acid alphabets exhibit an improved sensitivity and selectivity in fold assignment
Motivation: Many proteins with vastly dissimilar sequences are found to share a common fold, as evidenced in the wealth of structures now available in the Protein Data Bank. One idea that has found success in various applications is the concept of a reduced amino acid alphabet, wherein similar amino...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732308/ https://ncbi.nlm.nih.gov/pubmed/19351620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp164 |
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