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Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes
OBJECTIVE: Interleukin (IL)-1 impairs insulin secretion and induces β-cell apoptosis. Pancreatic β-cell IL-1 expression is increased and interleukin-1 receptor antagonist (IL-1Ra) expression reduced in patients with type 2 diabetes. Treatment with recombinant IL-1Ra improves glycemia and β-cell func...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Diabetes Association
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732140/ https://ncbi.nlm.nih.gov/pubmed/19542207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc09-0533 |
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