Nalaganje...

Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes

OBJECTIVE: Interleukin (IL)-1 impairs insulin secretion and induces β-cell apoptosis. Pancreatic β-cell IL-1 expression is increased and interleukin-1 receptor antagonist (IL-1Ra) expression reduced in patients with type 2 diabetes. Treatment with recombinant IL-1Ra improves glycemia and β-cell func...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Larsen, Claus M., Faulenbach, Mirjam, Vaag, Allan, Ehses, Jan A., Donath, Marc Y., Mandrup-Poulsen, Thomas
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732140/
https://ncbi.nlm.nih.gov/pubmed/19542207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc09-0533
Oznake: Označite
Brez oznak, prvi označite!