SAT-066 Effect Of Interleukin-1-receptor Antagonist On Hemodynamics And Renin-angiotensin-aldosterone System In Obese Individuals

Background: Interleukin (IL)-1 antagonism led to a decrease of systolic blood pressure (5mmHg) in obese individuals. The underlying mechanism is unknown. Based on experimental data in animals we hypothesised a blood-pressure lowering effect of IL-1-antagonism via modulation of the Renin-Angiotensin-...

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Udgivet i:J Endocr Soc
Main Authors: Urwyler, Sandrine, Ebrahimi, Fahim, Burkard, Thilo, Schuetz, Philipp, Poglitsch, Marko, Mueller, Beat, Donath, Marc, Christ-Crain, Mirjam
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2019
Fag:
Cardiovascular Endocrinology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551967/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-066
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