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Interleukin-1 Antagonists and Other Cytokine Blockade Strategies for Type 1 Diabetes
Proinflammatory cytokines stimulate adaptive immunity and attenuate T cell regulation and tolerance induction. They also profoundly impair β-cell function, proliferation, and viability, activities of similar importance in the context of type 1 diabetes (T1D). Detailed knowledge of the molecular mech...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SBDR - Society for Biomedical Diabetes Research
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740701/ https://ncbi.nlm.nih.gov/pubmed/23804271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2012.9.338 |
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