Interleukin-1 Antagonists and Other Cytokine Blockade Strategies for Type 1 Diabetes

Proinflammatory cytokines stimulate adaptive immunity and attenuate T cell regulation and tolerance induction. They also profoundly impair β-cell function, proliferation, and viability, activities of similar importance in the context of type 1 diabetes (T1D). Detailed knowledge of the molecular mech...

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Bibliographic Details
Main Author: Mandrup-Poulsen, Thomas
Format: Artigo
Language:Inglês
Published: SBDR - Society for Biomedical Diabetes Research 2012
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740701/
https://ncbi.nlm.nih.gov/pubmed/23804271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2012.9.338
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