The Role of SPINK1 in ETS Rearrangement Negative Prostate Cancers

ETS gene fusions have been characterized in a majority of prostate cancers, however the key molecular alterations in ETS negative cancers are unclear. Here we used an outlier meta-analysis (meta-COPA) to identify SPINK1 outlier-expression exclusively in a subset of ETS rearrangement negative cancers...

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Main Authors: Tomlins, Scott A., Rhodes, Daniel R., Yu, Jianjun, Varambally, Sooryanarayana, Mehra, Rohit, Perner, Sven, Demichelis, Francesca, Helgeson, Beth E., Laxman, Bharathi, Morris, David S., Cao, Qi, Cao, Xuhong, Andrén, Ove, Fall, Katja, Johnson, Laura, Wei, John T., Shah, Rajal B., Al-Ahmadie, Hikmat, Eastham, James A., Eggener, Scott E., Fine, Samson W., Hotakainen, Kristina, Stenman, Ulf-Håkan, Tsodikov, Alex, Gerald, William L., Lilja, Hans, Reuter, Victor E., Kantoff, Phillip W., Scardino, Peter T., Rubin, Mark A., Bjartell, Anders S., Chinnaiyan, Arul M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732022/
https://ncbi.nlm.nih.gov/pubmed/18538735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.04.016
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