The Role of SPINK1 in ETS Rearrangement Negative Prostate Cancers

ETS gene fusions have been characterized in a majority of prostate cancers, however the key molecular alterations in ETS negative cancers are unclear. Here we used an outlier meta-analysis (meta-COPA) to identify SPINK1 outlier-expression exclusively in a subset of ETS rearrangement negative cancers...

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Detalhes bibliográficos
Main Authors: Tomlins, Scott A., Rhodes, Daniel R., Yu, Jianjun, Varambally, Sooryanarayana, Mehra, Rohit, Perner, Sven, Demichelis, Francesca, Helgeson, Beth E., Laxman, Bharathi, Morris, David S., Cao, Qi, Cao, Xuhong, Andrén, Ove, Fall, Katja, Johnson, Laura, Wei, John T., Shah, Rajal B., Al-Ahmadie, Hikmat, Eastham, James A., Eggener, Scott E., Fine, Samson W., Hotakainen, Kristina, Stenman, Ulf-Håkan, Tsodikov, Alex, Gerald, William L., Lilja, Hans, Reuter, Victor E., Kantoff, Phillip W., Scardino, Peter T., Rubin, Mark A., Bjartell, Anders S., Chinnaiyan, Arul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732022/
https://ncbi.nlm.nih.gov/pubmed/18538735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.04.016
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