Prognostic Value of PAI1 in Invasive Breast Cancer: Evidence That Tumor-Specific Factors Are More Important Than Genetic Variation in Regulating PAI1 Expression

Plasminogen activator inhibitor-1 (PAI1) can promote cancer progression, and its protein expression in tumors is an independent indicator of poor prognosis in many forms of cancer. Here, we show that high PAI1 mRNA levels also predict for shorter overall survival in two independent breast cancer dat...

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Bibliographic Details
Main Authors: Sternlicht, Mark D., Dunning, Alison M., Moore, Dan H., Pharoah, Paul D.P., Ginzinger, David G., Chin, Koei, Gray, Joe W., Waldman, Frederic M., Ponder, Bruce A.J., Werb, Zena
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731792/
https://ncbi.nlm.nih.gov/pubmed/17119035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-06-0351
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