Prognostic Value of PAI1 in Invasive Breast Cancer: Evidence That Tumor-Specific Factors Are More Important Than Genetic Variation in Regulating PAI1 Expression

Plasminogen activator inhibitor-1 (PAI1) can promote cancer progression, and its protein expression in tumors is an independent indicator of poor prognosis in many forms of cancer. Here, we show that high PAI1 mRNA levels also predict for shorter overall survival in two independent breast cancer dat...

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Detalhes bibliográficos
Main Authors: Sternlicht, Mark D., Dunning, Alison M., Moore, Dan H., Pharoah, Paul D.P., Ginzinger, David G., Chin, Koei, Gray, Joe W., Waldman, Frederic M., Ponder, Bruce A.J., Werb, Zena
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731792/
https://ncbi.nlm.nih.gov/pubmed/17119035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-06-0351
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