Increased Risk for CNS Relapse in Pre-B Cell Leukemia with the t(1;19)/TCF3-PBX1

To evaluate the impact of contemporary therapy on the clinical outcome of children with pre-B acute lymphoblastic leukemia (ALL) and the t(1;19)/TCF3/PBX1, we analyzed 735 patients with B-cell precursor ALL treated in four successive protocols at St. Jude Children’s Research Hospital. The 41 patient...

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Autori principali: Jeha, Sima, Pei, Deqing, Raimondi, Susana C., Onciu, Mihaela, Campana, Dario, Cheng, Cheng, Sandlund, John T., Ribeiro, Raul C., Rubnitz, Jeffrey E., Howard, Scott C., Downing, James R., Evans, William E., Relling, Mary V., Pui, Ching-Hon
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731684/
https://ncbi.nlm.nih.gov/pubmed/19282835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.42
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