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Human Pituitary Contains Dual Cathepsin L and Prohormone Convertase Processing Pathway Components Involved in Converting POMC into the Peptide Hormones ACTH, α-MSH, and β-Endorphin

The production of the peptide hormones ACTH, α-MSH, and β-endorphin requires proteolytic processing of POMC which is hypothesized to utilize dual cysteine and subtilisin-like protease pathways, consisting of the secretory vesicle cathepsin L pathway and the well-known subtilisin-like prohormone conv...

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Detalhes bibliográficos
Main Authors: Hook, Vivian, Funkelstein, Lydiane, Toneff, Thomas, Mosier, Charles, Hwang, Shin-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731682/
https://ncbi.nlm.nih.gov/pubmed/19343278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12020-009-9163-5
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